Upstate South Carolina Vacations from $713
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Your Upstate South Carolina Vacation
When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.
The Latest Upstate South Carolina vacation packages
Price found within the past 48 hours. Click for updated prices.
Fox Run at Lake Lure
Save 100% on your flight
Price was $1,000, price is now $713 per person
$713
per person
Jul 14 - Jul 21
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Asheville (AVL)
9.2/10 Wonderful! (201 reviews)
Clean rooms, a well-equipped kitchen, and a very relaxing atmosphere
Reviewed on May 4, 2026
The Radical Asheville, Tapestry Collection by Hilton
River Arts District
Save 100% on your flight
Price was $1,149, price is now $792 per person
$792
per person
Jul 14 - Jul 21
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Asheville (AVL)
9.6/10 Exceptional! (547 reviews)
Really sweet place to stay. Rooms are deluxe and the staff was really kind and helpful. Nice area walkable to the arts district and good coffee place
Reviewed on May 10, 2026
The Windsor Boutique Hotel
Downtown Asheville
Save 100% on your flight
Price was $2,009, price is now $1,473 per person
$1,473
per person
Jul 14 - Jul 21
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Asheville (AVL)
9.8/10 Exceptional! (592 reviews)
Rooms are spacious, wonderfully appointed with soft robes and good coffee. Very comfortable beds. The location is perfect, close to shops, spas, breweries, restaurants. Staff is friendly and helpful. Would absolutely stay here again.
Reviewed on Apr 4, 2026
The Omni Grove Park Inn & Spa
Grove Park- Sunset
Save 100% on your flight
Price was $2,557, price is now $1,921 per person
$1,921
per person
Jul 14 - Jul 21
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Asheville (AVL)
9.2/10 Wonderful! (1,006 reviews)
The experience of Grove Park Inn is unique. From the fireplaces to the Blue Ridge dininging room to the attentive staff. My daughter was the proposed to on the Sunset Terrace yesterday and everyone applauded
If you want a magical experience go to GPI!
Reviewed on May 10, 2026
Grand Bohemian Lodge Asheville, Autograph Collection®
Biltmore Village
Save 100% on your flight
Price was $1,529, price is now $1,152 per person
$1,152
per person
Jul 14 - Jul 21
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Asheville (AVL)
9.2/10 Wonderful! (932 reviews)
Friendly staff, very clean rooms. Make sure when you book you clarify what type of room you want (tub, balcony, etc) . We didn’t specify because we booked online, and we were given a non tub room when we wanted a tub room. The staff made the change for us, no problem, which was great!
Reviewed on May 9, 2026
Don't see what you're looking for?
See all available trips from Columbus to Upstate South Carolina
View all tripsWhere to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
2 out of top 10 points of interest in this area
5/5(657 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Discover the most popular places to visit in Upstate South Carolina
Clemson University
5/5(423 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
4.5/5(594 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.
Fred W. Symmes Chapel
5/5(12 reviews)
You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.
What to do in Upstate South Carolina
Upstate South Carolina Hotel Deals
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$105 nightly
The price is $116 total per night from May 17 to May 18
$116 total
May 17 - May 18
Total with taxes and fees
8.6/10 Excellent! (1,012 reviews)
Great
Reviewed on May 10, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $131 total per night from May 24 to May 25
$131 total
May 24 - May 25
Total with taxes and fees
9/10 Wonderful! (1,198 reviews)
Everything was awesome
Reviewed on May 10, 2026
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$361 nightly
The price is $396 total per night from May 31 to Jun 1
$396 total
May 31 - Jun 1
Total with taxes and fees
9.6/10 Exceptional! (491 reviews)
The hotel is centrally located- the staff is attentive, they love my dog!!! The place is clean and the outdoor bar is lovely. Would definitely recommend-
Reviewed on May 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Upstate South Carolina Vacation Packages
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
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- Conestee Nature Preserve
- Mauldin Vacations
- Visit Mauldin
- Cu Intl. Center for Automotive Research
- Discovery Island Water Park
- Terrace Shopping Center
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- Gravitopia Trampoline Arena
- Green Forest Park
- Mcalister Square
- Old Towne Shopping Center
- 7th Inning Splash Waterpark
- Lakeside Park
- Lewis Plaza Shopping Center
- Runway Park at GMU
- Prisma Health Greenville Memorial Hospital
- Roper Mountain Science Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
