Upstate South Carolina Vacations from $565
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Your Upstate South Carolina Vacation
When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.
The Latest Upstate South Carolina vacation packages
Price found within the past 48 hours. Click for updated prices.
Element Asheville Downtown
Downtown Asheville
Price was $812, price is now $565 per person
$565
per person
Feb 12 - Feb 16
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Asheville (AVL)
9.4/10 Exceptional! (438 reviews)
Most Staff was very friendly! Breakfast was good except when they ran out early and the coffee machine was broken. Relax hour was good except when the wine keg was broken.
Reviewed on Nov 28, 2025
The Horse Shoe Farm
Save 100% on your flight
Price was $2,121, price is now $1,328 per person
$1,328
per person
Mar 5 - Mar 9
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Asheville (AVL)
9.6/10 Exceptional! (7 reviews)
Every staff member went out of his/her way to make us more comfortable.
Reviewed on Jul 27, 2024
The Restoration Asheville
Downtown Asheville
Save 100% on your flight
Price was $1,213, price is now $835 per person
$835
per person
Mar 3 - Mar 8
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Asheville (AVL)
9.8/10 Exceptional! (984 reviews)
Great staff, clean lovely rooms, multiple onsite restaurants, unbeatable location. And the breakfast basket is a nice touch.
Reviewed on Dec 22, 2025
Hotel Hartness
Save 100% on your flight
Price was $1,240, price is now $864 per person
$864
per person
Mar 10 - Mar 15
found 1 day ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Greenville (GSP)
9.8/10 Exceptional! (613 reviews)
Beautiful hotel, very nice staff, lots of space to work remotely
Reviewed on Dec 15, 2025
The Windsor Boutique Hotel
Downtown Asheville
Save 100% on your flight
Price was $975, price is now $681 per person
$681
per person
Jan 23 - Jan 27
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Asheville (AVL)
9.8/10 Exceptional! (543 reviews)
Wonderful hotel, clean, spacious, comfortable, and close to restaurants and shopping. Friendly and helpful staff.So many little extras. Will definitely be back.
Reviewed on Dec 15, 2025
Don't see what you're looking for?
See all available trips from Columbus to Upstate South Carolina
View all tripsWhere to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
3 out of top 10 points of interest in this area
5/5(654 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Discover the most popular places to visit in Upstate South Carolina
Clemson University
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.
Memorial Stadium
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.
What to do in Upstate South Carolina
Epic City Scavenger Hunt in Garden Grove by Operation City Quest
$10
per adult
Upstate South Carolina Hotel Deals
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $110 total per night from Dec 29 to Dec 30
$110 total
Dec 29 - Dec 30
Total with taxes and fees
8.2/10 Very Good! (1,001 reviews)
Amazing staff and clean room
Reviewed on Dec 7, 2025
Homewood Suites by Hilton Greenville Downtown
950 South Main Street Greenville SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $135 total per night from Jan 1 to Jan 2
$135 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
9.4/10 Exceptional! (1,009 reviews)
Beautiful hotel
Reviewed on Dec 21, 2025
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $107 total per night from Dec 30 to Dec 31
$107 total
Dec 30 - Dec 31
Total with taxes and fees
8.8/10 Excellent! (1,003 reviews)
Food was fresh and there was a cook making omelettes to order
Reviewed on Dec 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Upstate South Carolina Vacation Packages
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
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- Lakeside Park
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- Runway Park at GMU
- Prisma Health Greenville Memorial Hospital
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
