Name: Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Price range: $105 total
Rating: 8.4

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Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

The Latest Upstate South Carolina vacation packages

Price found within the past 48 hours. Click for updated prices.

Holiday Inn Asheville East-Blue Ridge PKWY by IHG

per person

Nov 1 - Nov 4

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Asheville (AVL)

9.4/10 Exceptional! (1,002 reviews)

The bed was comfortable. They allowed us a late check-out.

Reviewed on Aug 15, 2025

Hilton Garden Inn Asheville Downtown

Downtown Asheville

Save 100% on your flight

per person

Nov 1 - Nov 4

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Asheville (AVL)

9.2/10 Wonderful! (848 reviews)

nice size room, friendly staff

Reviewed on Aug 14, 2025

Bluegreen Vacations Blue Ridge Village an Ascend Resort

Save 100% on your flight

per person

Oct 16 - Oct 19

found 10 hours ago

Roundtrip flight included

Boston (BOS) to Asheville (AVL)

9.2/10 Wonderful! (860 reviews)

We really enjoyed our stay here! There are great activities for your kids and the staff are very helpful and friendly! This location is close to many attractions such as grandfather Mountain and Linville Falls. Hope to come here again.

Reviewed on Aug 8, 2025

Grand Bohemian Lodge Asheville, Autograph Collection®

Biltmore Village

Save 100% on your flight

per person

Nov 1 - Nov 4

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Asheville (AVL)

9.2/10 Wonderful! (870 reviews)

My wife and I loved this hotel. Right at the front entrance to Biltmore which is why we came to Asheville. Staff were nice and professional. The food there was excellent. We really enjoyed the room. We will stay here again.

Reviewed on Jun 21, 2025

The Windsor Boutique Hotel

Downtown Asheville

Save 100% on your flight

per person

Nov 1 - Nov 4

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Asheville (AVL)

9.8/10 Exceptional! (523 reviews)

We loved the quaintness of the property and how central it was to walk all over town. The staff was fantastic too. Definitely our place for when we visit.

Reviewed on Aug 8, 2025

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

Greenville featuring autumn leaves, a garden and a bridge

Greenville Downtown

3 out of top 10 points of interest in this area

5/5(654 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Discover the most popular places to visit in Upstate South Carolina

Clemson University

Walk around the campus of Clemson University, a top university in Clemson. Experience the area's theater scene or attend a football game.

Lake Keowee

Commune with nature and explore the great outdoors at Lake Keowee during your travels in Salem. While you're in the area, wander around the college campus.

Falls Park on the Reedy

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

What to do in Upstate South Carolina

Epic City Scavenger Hunt in Garden Grove by Operation City Quest

$10

per adult

Just Desserts Tour In Greenville

$80

per adult

Delicious breakfast on a sunny Saturday morning on the terrace

Small-Group Walking Tour in Greenville with Breakfast

$80

per adult

100% of travellers recommend

See all activities in Upstate South Carolina

Upstate South Carolina Hotel Deals

Hilton Greenville

45 W Orchard Park Dr, Greenville, SC

Fully refundableReserve now, pay when you stay

$84 nightly

$93 total

Aug 21 - Aug 22

Total includes taxes and fees

8/10 Very Good! (1,003 reviews)

"Everything was excellent."

Reviewed on Aug 15, 2025

Hyatt Regency Greenville

220 N Main St, Greenville, SC

Fully refundableReserve now, pay when you stay

$139 nightly

$153 total

Aug 24 - Aug 25

Total includes taxes and fees

8.6/10 Excellent! (1,001 reviews)

"The restaurant was under construction and had limited menu and no food service at bar The food I had was very tasty"

Reviewed on Aug 11, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

851 Congaree Rd, Greenville, SC

Fully refundable

$95 nightly

$105 total

Aug 22 - Aug 23

Total includes taxes and fees

8.4/10 Very Good! (1,000 reviews)

"Staff was great hotel was clean"

Reviewed on Aug 8, 2025

See all 2,780 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.