Upstate South Carolina Vacation Packages 2026 from $472

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Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

The Latest Upstate South Carolina vacation packages

Price found within the past 48 hours. Click for updated prices.

Highlands Houses For Rent

Save 100% on your flight

$472

per person

Nov 12 - Nov 15

just found

Roundtrip flight included

Miami (MIA) to Greenville (GSP)

10/10 Exceptional! (3 reviews)

Amazing little house in the woods! We absolutely loved it. Close enough to walk to town while also feeling secluded and woodsy.

Reviewed on Jan 21, 2026

The Restoration Asheville

Downtown Asheville

$826

per person

Dec 1 - Dec 5

found 21 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Asheville (AVL)

9.8/10 Exceptional! (1,214 reviews)

The Windsor Boutique Hotel

Downtown Asheville

Save 100% on your flight

$838

per person

Nov 15 - Nov 19

found 1 day ago

Roundtrip flight included

Fort Lauderdale (FLL) to Asheville (AVL)

9.8/10 Exceptional! (614 reviews)

AutoCamp Asheville

$482

per person

Nov 11 - Nov 14

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Asheville (AVL)

9.6/10 Exceptional! (11 reviews)

Absolutely wonderful! We loved our hilltop view, the fresh air, and the complimentary coffee in the morning. Our room was pristine and the staff were exceptional. The property is gorgeous, quiet, and peaceful. Downtown is easily accessible while still feeling removed (which is ideal for us). We were surprised firewood wasn’t included with the room, but it was worth the extra fee. And breakfast options are limited in my opinion, so we opted to eat downtown instead on our second day there.

Reviewed on Sep 24, 2026

Albemarle Inn

Grove Park- Sunset

$726

per person

Dec 1 - Dec 5

found 21 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Asheville (AVL)

9.2/10 Wonderful! (488 reviews)

Beautiful place. We had a very nice time and I am planning on coming back.

Reviewed on Aug 24, 2026

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Greenville Downtown

2 out of top 10 points of interest in this area

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by Piazza Bergamo or The Peace Center might round out your trip.

Nicholtown

If you're spending some time in Nicholtown, Swamp Rabbit Trail and Pleasantburg Shopping Center are top sights worth seeing.

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Overbrook Historic District

While Overbrook Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bon Secours Wellness Arena and Beattie House.

A cityscape with a mix of modern and historic buildings, a large parking lot, and a highway.

West End

Arts and entertainment thrive in this Greenville neighborhood, with cultural events at the Peace Center and baseball games at Fluor Field at the West End. Don't miss Falls Park on the Reedy and the picturesque Liberty Bridge crossing the river.

Hampton-Pinckney Historic District

Hampton-Pinckney Historic District is well-liked for its historic sites. If you'd like to do some sightseeing in the greater Greenville area, you might plan a trip to The Children’s Museum of the Upstate or The Peace Center.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

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Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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What to do in Upstate South Carolina

Spooky & Haunted Paranormal Bar Crawl Downtown Greenville

Greenville Haunted Bar Tour

$28

per adult

100% of travellers recommend

Just Desserts Tour In Greenville

$95

per adult

Saturday Evening Craft Cocktail Tour

$105

per adult

100% of travellers recommend

See all activities in Upstate South Carolina

Upstate South Carolina Hotel Deals

Hilton Greenville

45 W Orchard Park Dr Greenville SC

Fully refundableReserve now, pay when you stay

$117 nightly

$129 total

Oct 11 - Oct 12

Total with taxes and fees

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

Fully refundableReserve now, pay when you stay

$108 nightly

$120 total

Oct 4 - Oct 5

Total with taxes and fees

9/10 Wonderful! (1,395 reviews)

"I was very disappointed in the quality of this embassy suites. I have stayed at many and never experienced the poor conditions of the room. The A/C had to be broken and the tub was gross. The staff was decent."

Reviewed on Sep 24, 2026

Hyatt Place Greenville/Haywood

40 W Orchard Park Dr Greenville SC

Fully refundableReserve now, pay when you stay

$82 nightly

$91 total

Oct 18 - Oct 19

Total with taxes and fees

See all 3,090 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.